New database of Derived No-Effect Levels (DNELs) established under the REACH Regulation

The German Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA) has launched a new database of  Derived No-Effect Levels (DNELs): the GESTIS DNEL database.

This database has been set up upon request of the German Social Accident Insurance Institutions and with their specialised support.



According to the EU Regulation concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), DNELs are levels of exposure to a substance above which humans should not be exposed and have to be established by manufacturers and importers. Derived from the human health hazard assessment as part of the REACH requirements, they are exposure levels below which it is considered that adverse effects will not occur for a particular route and duration and frequency of exposure.